Intelligent human-computer interaction (HCI) integrates versatile tools such as perceptual recognition, machine learning, affective computing, and emotion cognition to enhance the ways humans interact with computers. Facial expression analysis is one of the essential medium of behavior interpretation and emotion modeling. In this paper, we modify and develop a reconstruction method utilizing Principal Component Analysis (PCA) to perform facial expression recognition. A framework of hierarchical radial basis function network (HRBFN) is further proposed to classify facial expressions based on local features extraction by PCA technique from lips and eyes images. It decomposes the acquired data into a small set of characteristic features. The objective of this research is to develop a more efficient approach to discriminate between seven prototypic facial expressions, such as neutral, smile, anger, surprise, fear, disgust, and sadness. A constructive procedure is detailed and the system performance is evaluated on a public database "Japanese Females Facial Expression (JAFFE)." We conclude that local images of lips and eyes can be treated as cues for facial expression. As anticipated, the experimental results demonstrate the potential capabilities of the proposed approach.